Detoxamin's powerful and patented formula results in EDTA reaching your circulatory system with much less alteration, much greater concentrations.


Detoxamin EDTA chelation avoids hepatic first-pass effect and bypasses first-pass metabolism. Results in EDTA reaching your circulatory system with much less alteration, much greater concentrations.

Be Aware that the average body holds 1,000% percent more lead today than 100 years ago simply because of the environment we live in. Chelation therapy is a safe, effective, inexpensive alternative to drugs and surgeries.

Protect Yourself and your family with the most effective self-administered Ca-EDTA therapy available. Detoxamin Ca-EDTA chelation therapy is just as effective as traditional intravenous methods-without any needles, repeated office visits, or time consuming intravenous treatments. At about 30% of the traditional cost.

Detoxamin edta suppositories are more affordable, helps with heavy metal detox, the best metal detox available, more effective than oral chelation, much less chelation therapy side effects, for a lower chelation therapy cost, more affordable metal chelation, has less heavy metal detox symptoms,
  • Time-release

    Detoxamin has a time-release mechanism that allows the EDTA to absorb through the colon wall over an eighty-minute period while you sleep. Almost all the blood from the rectum makes its way to the superior hemorrhoidal veins, a tributary of the portal system, so that absorption through the rectal wall carries the EDTA in Detoxamin to the portal vein (see figure). The lower and middle hemorrhoidal veins bypass the liver-and do not undergo first pass metabolism. This means that the EDTA in Detoxamin goes directly to the organs of your body without being filtered through the liver first. Because of this, the EDTA contained in Detoxamin is very productive.

  • Many advantages

    Detoxamin offers many advantages both over the expensive intravenous method of EDTA chelation. With the use of needles via the intravenous method, and risk of AIDS and other communicable blood-borne diseases, Detoxamin is becoming the logical choice over I.V. EDTA chelation and the poorly absorbed oral EDTA. The rectum has a more neutral pH and is not as acidic as the stomach, which makes this area much better for EDTA absorption because it is not buffered and has a neutral pH, unlike the stomach. It also has very little enzymatic activity, thus enzymatic degradation does not occur. 

  • Direct organ delivery

    Detoxamin also introduces EDTA directly into the systemic circulation, efficiently bypassing the portal circulation and the liver metabolism on the first pass. Rectal absorption may also occur through the lymphatic system and, in some cases, largely through the blood via the vena cava.



Medical compendium of scientific and clinical studies on Detoxamin Chelation Suppositories. Includes a compilation of research documents and publications on pharmacokinetics, safety and efficacy of Detoxamin.



Heavy metals accumulate in various tissues, associated with increases in todays diseases. Reducing heavy metals from the body has been a challenge to modern medicine. With the advent of EDTA chelation, removing toxic metals is now a reality, but the invasive IV method is burdensome and expensive. 



Detoxamin in conjunction with Friends of Lead Free Children, a non-profit organization connected to Columbia University and Fordham University, assisted in the search. A residential neighbourhood in Haina, Dominican Republic was selected. The neighbourhood was located adjacent to a battery recycling plant where the kids would play.


Did you ever wonder how researchers get rats with cancer of the prostate so they can study the effects of prescription drugs? They dose them with cadmium. Why? Because it has a remarkable ability to zero in on the testicles as target organs. Many studies have been done on workers involved in the cadmium industry (cadmium batteries, welders, fabricated metal products, etc.) showing they have up to four times the increased incidence of prostate cancer compared to the average male. Cadmium, an environmental heavy metal that is commonly found in our foods, can be the cause of prostate symptoms. This toxic heavy metal cannot be avoided and once inside the body, damages enzymes and mimics the chemistry of disease.

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Detoxamin with EDTA. Get it now!

EDTA has been proven to protect cell membranes, DNA and enzyme systems by reducing the destructive effects of free radicals.

Free radicals are reactive molecules that are unstable because they are missing an electron. In an effort to replace their lost electron, they frantically bump into and damage the molecules that make up the cells in your body. In the process, they cause oxidation of body tissues. It's impossible to be alive and not have some oxidative damage, because free radicals are produced by normal processes in the body, such as the production of energy and immune function.

Free radicals also come from environmental sources including heavy metals, household chemicals, ultraviolet radiation, tobacco smoke, food additives, foods that have been fried in oil that's been used over and over again (typical in many fast-food restaurants), and other pollutants. Once free radicals are released, they will multiply exponentially in chain reactions, unless they are stopped by antioxidants.

EDTA has been shown to be a powerful antioxidant that destroys free radicals - the culprits of atherosclerosis, cardiovascular disease, Alzheimer's disease, and some types of cancer.

Some of the most dangerous emerging health challenges society is facing today are directly related to environmental oxidative toxins.

Detoxamin Chelation Suppositories. A Novel Approach For Removing Heavy Metals In Clinical Practice.

Benefits Of EDTA Chelation Therapy in Arteriosclerosis

A Retrospective Study Of 470 Patients
  • 1. Benefits of EDTA Chelation Therapy in Arteriosclerosis a Retrospective Study of 470 Patients

    by C. Hancke, MD, and K. Flytlie, MD

  • 2. A Pilot Double Blind Study of Sodium Magnesium EDTA in Peripherral Vascular Disease

    by Efrain Olszewer, MD, Fuad Calil Sabbag, MD, and James P. Carter, MD, DrPH New Orleans, Louisiana

  • 3. EDTA Chelation Therapy Efficacy in Arteriosclerotic Heart Disease

    by H. Richard Casdorph, MD, PhD

  • 4. EDTA Chelation Therapy III Treatment of Peripheral Arterial Occlusion an Alternative to Amputation

    by H. Richard Casdorph, MD, PhD and Charles H. Farr, MD, PhD

  • 5. EDTA Chelation Therapy in Chronic Degenerative Disease


  • 6. The Correlation Between EDTA Chelation Therapy and Improvement in Cardiovascular Function A Meta Analysis

    by L. Terry Chappell, MD, and John P. Stahl, PhD

  • 7. 6 Children with Lead Poisoning

    by John A, Friedman, MD, Howard L. Weinberger, MD

  • 8. A Nonsurgical Approach to Obstructive Carotid Stenosis Using EDTA Chelation

    by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP, and R.K. Barber, BS, ACSM, ETT

  • 9. Absorbtion of Drugs from the Rat Colon by Lewis S. Schanker

    by Lewis S. Schanker

  • 10. An Observation of the Effect of EDTA Chelation and Supportive Multivitamin Trace Mineral Supplementation onBlood Platelet Volume a Brief

    by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP, and R.K. Barber, BS, ACSM, ETT

  • 11. An Oculocerebrovasculometric Analysis of the Improvement in Arterial Stenosis Following EDTA Chelation Therapy

    by E.W. McDonagh, DO, FACGP, C.J. Rudolph, DO, PhD, E. Cheraskin, MD, DMD

  • 12. Beneficial Effects of Zinc Supplementation During Chelation Treatment of Lead Intoxication in Rats

    by S.J.S. Flora and S.K. Tandon

  • 13. Carotid Restenosis a Case for EDTA Chelation

    by H. Joseph Holliday, MD, FACA, RVT

  • 14. Chelation Therapy a Survey of Treatment Outcomes and Selected SocioMedical Factors

    by Wesley J. Adams, PhD, and Charles T. McGee, MD

  • 15. Chelation Therapy of Occlusive Arteriosclerosis in Diabetic Patients

    by Carlos P. Lamar, MD, F.I.C.A.

  • 16. Chronic Diseases A Practical Method for the Reduction of Plasma Cholesterol in Man

    by Henry A. Schroeder, M.D.

  • 17. Current Status of EDTA Chelation Therapy in Occlusive Arterial Disease , MD

    by Elmer M. Cranton, MD, James P. Frackelton

  • 18. Demographic Data and Treatment of Small Companion Animals With Lead Poisoning 347 Cases 1977 to 1986

    by Rhea V. Morgan, DVM; Laurie K. Pearce, DVM; Frances M. Moore, DVM; Thomas Rossi, DVM, MS

  • 19. Disappearance of Immune Deposits with EDTA Chelation Therapy in a Case of IgA Nephropathy

    by Ja-Liang Lin, MD

  • 20. Disintergration of Retroviruses by Chelating Agents

    by V. Wunderlich and G. Sydow

  • 21. EDTA Chelation Treatment for Vascular Disease A Meta Analysis Using Unpublished Data

    by L. Terry Chappell, MD, John P. Stahl, PhD, and Ronald Evans, MA

  • 22. Effect of EDTA Chelation and Supportive Multivitamin Trace Mineral Supplementation Chronic Lung Disorders A Study of FVC and FEV

    by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP, and Rhonda.K. Barber, BS, ACSM, ETT

  • 23. Effect of EDTA Chelation and Supportive Multivitamin Trace Mineral Supplementation on Carotid Circulation Case Report

    by C.J. Rudolph, DO, PhD, E.W. McDonagh, DO, ACGP

  • 24. Effect of EDTA Chelation Therrapy Plus Multivitamintrace Mineral Supplementation Upon Vascular Dynamics Ankle Brachial Doppler Systolic Blood Pressure Ratio

    by E.W. McDonagh, DO, C.J. Rudolph, DO, E Cheaskin, MD, DMD

  • 24. Elevated Lead Levels in a Patient with Sickle Cell Disease and Inappropriate Secretion of Antidiuretic Hormone

    by Carlos R. Suarez, MD, Lehman E. Black III, MD, R. Morrison Hurley, MD

  • 25. Lead Nephropathy Gout and Hypertension

    by Vicihi Batuman, MD, FACP

  • 26. Lead Toxicity Chelation Therapy New Findings

    by R. Gooneratne and A. Olkowski

  • 27. Magnetic Resonance Imaging Evidence of a Reduction in Disc Herniation Using a Combination of EDTA Chelation and Joint Reconstructive Therapy

    by C.J. Rudolph, DO, PhD, FACAM, E.W. McDonagh, DO, ACGP, FACAM

  • 28. Mineral Excretion Associated with EDTA Chelation Therapy

    by Hugh D. Riordan, M.D., Emanuel Cheraskin, M.D., D.M.D., and Marvin Dirks, B.D., M.A.

  • 29. Visual Field Evidence of Macular Degeneration Reversal Using a Combination of EDTA Chelation and Multiple Vitamin and Trace Mineral Therapy

    by C.J. Rudolph, DO, PhD, FACAM, R.T. Samuels, OD, and E.W. McDonagh, DO, ACGP, FACAM

  • 30. Potential Uses of Chelation Methods in the Treatment of Cardiovascular Diseases

    by J. Roderick Kitchell, Lawrence E. Meltzer and Marvin J. Seven

  • 31. Reduction of Elevated Plasma Lipid Levels in Artherosclerosis following EDTA Therapy

    by J. H. Olwin and J. L. Koppel

  • 32. Safety Evalutation Studies of Calcium EDTA

    by Bernard L. Oser, Mona Oser and Howard C. Spencer

  • 33. The "Clinical Change" in Patients Treated with EDTA Chelation Plus Multivitamin/Trace Mineral Supplementation

    by Edward W. McDonagh, D.O., Charles J. Rudolph, Ph.D., D.O., and Emanuel Cheaskin, M.D., D.M.D.

  • 34. The Correlation Between EDTA Chelation Therapy and Improvement in Cardiovascular Function: A Meta-Analysis

    by L. Terry Chappell, MD, and John P. Stahl, PhD

  • 35. The Current Status of EDTA Chelation Therapy

    by Elmer M. Cranton, MD

  • 36. The Effect of Calcium Chelation on Cardiac Arrythmias and Conduction Disturbances

    by Sidney Jick, M.D. and Robert Karsh, M.D.

  • 37. The Effect of EDTA Chelation Therapy Plus Supportive Multivitamin Trace Mineral Supplementation Upon Renal Function: A Study in Blood Urea Nitrogen (BUN)

    by E.W. McDonagh, DO, C.J. Rudolph, DO, PhD, E. Cheraskin, MD, DMD

  • 38. The Effect of EDTA Chelation Therapy Plus Supportive Multivitamin Trace Mineral Supplementation Upon Renal Function: A Study in Serum Creatinine

    by EW McDonagh, DO, CJ Rudolph, PhD, DO, E Cheraskin, MD, DMD

  • 39. The Effects of Thiamin on Lead Metabolism: Whole Body Retention of Lead-203

    by Jin Suk Kim, Donald L. Hamilton, Barry R, Blakley, and Colin G. Rousseaux

  • 40. The Efficacy of Chelation Therapy and Factors Influencing Mortality in Lead Intoxicated Petrol Sniffers

    by C. B. Burns PhD, B. Currie

  • 41. Treatment of Occlusive Vascular Disease with Disodium Ethylene Diamine Tetraacetic Acid (EDTA)

    by Norman E. Clarke, Sr. M.D., Norman E. Clarke Jr. M.D. and Robert E. Mosher, PhD

  • 42. Proof of EDTA's Permeability by way of the Colon

    by M. Ella, R Behrens, C Northrop, P Wraight and G. Neale Dunn Clinical Nutrition Centre and New Addenbrooke's Hospital, Cambridge, U.K.

Other references

1. 1. Press Conference October 17, 2000. Statement by William J. Walsh, Ph.D. Director of Beethoven Research Project. The Health Research Institute and Pfeiffer Treatment Center, Naperville, Illinois.(; accessed 6/17/07).
2. 2. "Full of Lead" by Stephen Janis. Baltimore City Paper; 3/9/2005.
3.; accessed 6/26/07).
4. "Study Finds Correlation Between Fluorides in Water and Lead Levels." Press release from Dartmouth News; August 31, 1999. Roger Masters, Nelson A. Rockefeller Professor of Government Emeritus at Dartmouth College. (; accessed 4/23/07).
5. "The Mad Hatter Syndrome: mercury and biological toxicity" by Leigh Erin Connealy, MD. January 06, 2006. (; accessed 4/23/07).
6. "45 States Have Issued Mercury Advisories: coal-fired power plants." Source: Environmental Protection Agency and Department of Natural Resources.
7. "Mercury and Fish Advisories lssued for Nine More Waterways. Source: De Ridder Beauregard Daily News. Quoted from The Louisiana Department of Health and Hospitals Environmental Quality.
8. "Dangerous Lead Levels Found in More Homes." Source: Cincinnati Enquirer. Quoted from the EPA.
9. "Lead Linked to Premature Deaths in Adults: Early Exposure = 46% Higher Mortality." Source: The Baltimore Sun. Quoted from the CDC. =
10. “California Sues Over Heavy Metal Fish." Source: Business Report. Quoted from the California Attorney General.
11. "EPA Doubles Estimates of Children with Mercury in Blood." Source: The News-Press. Quoted from Department of Environmental Protection.
12. "CDC Vaccine Data Leads Scientists to Shocking Discovery: Possible Autism/Neurological Link." Source: Yahoo News-Quoted from the CDC.
13. "Chromated Copper Arsenate: CCA-Treated Lumber Poses Danger from Arsenic." Toxico Sci. 2004 Jun;79(2):287-95.
14. "FDA Warns Pregnant Women to Limit Tuna." Source: Richard Simmons; Los Angeles Times.3/2004.
15. Schober SE, Mirel LB, Graubard BI, Brody DJ, Flegal KM. Blood Lead Levels and Death from All Causes, Cardiovascular Disease, and Cancer: Results from the NHANES III Mortality Study. Environ Health Perspect. 2006 October, 114(10): 1538-1541
16. Doll R, Fishbein L, Infante P, Landrigan P, Lloyd JW, Mason TJ, Mastromatteo E, Norseth T, et al. Problems of epidemiological evidence. Environ. Health Perspect. 1981;40:11- 20.
17. Kazantzis G. Role of cobalt, iron, lead, manganese, mercury, platinum, selenium and titanium in carcinogenesis. Environ/ Health Perspect. 1981;40:143-161.
18. "Smaller power sources on the horizon" by Sandeep Junnakar. Nov. 13, 2002. [http://CNET; 6/26/2007].
19. "Historical Perspectives on the Development of Chelation Therapies." An Extended Compendium Prepared for the Advanced Training Seminar on Heavy Metal Toxicology. September 1998. Sponsored by the Great Lakes College of Medicine. Prepared by John Parks Trowbridge MD, FACAM, Diplomate ABCT. Permission granted to Life Center Houston to publish on the website.
20. "Detoxify or Die." Sherry A. Rogers, MD. Sand Key Company, lnc. Sarasota, FL. 2002.
21. Multiple Sclerosis Symptoms. (National Multiple Sclerosis Society).
22. Bernard S, Enayati A, Binstock T, Roger H, Redwood L, McGinnis W. Autism: A Unique Type of Mercury Poisoning. ARC Research. April, 2000.
23. Ibid.
24. Dartmouth Toxic Metal Research Program. (A program of the Center for Environmental Health Sciences at Dartmouth). Report: Dartmouth Toxic Metals Research Program: The facts on cadmium.
25. Oral Chelation and Nutritional Replacement Therapy for Chemical & Heavy Metal Toxicity and Cardiovascular Disease by Maile Pouls, Ph.D. (Townsend Letter, 1999).
26. Nickel, nickel carbonyl, and some nickel compounds Health and Safety Guide. World Health Organization, Geneva 1991.
27. Steven Marcus, MD, Professor, Department of Preventive Medicine and Community Health, Associate Professor, Department of Pediatrics, New Jersey Medical School, University of Medicine and Dentistry of New Jersey; Executive and Medical Director, New Jersey Poison Information and Education System; Consulting Staff, Departments of Pediatrics and Internal Medicine, University Hospital, University of Medicine and Dentistry of New Jersey; Consulting Staff, Department of Pediatrics, Newark Beth Israel Medical Center : Toxicity, Arsenic.
28. Clifford Spanierman, MD, Consulting Staff, Departments of Emergency Medicine and Pediatrics, Lutheran General Hospital of Oak Brook, Advocate Health System: " Toxicity, lron
29. Chen F, Shi X. "lntracellular signal transduction of cells in response to carcinogenic metals." Crit. Rev. Oncol. Hematol. 2002 Apr;42(1):105- 21.
30. Wang Suwei, Shi Xianglin. "Mechanisms of 'Cr(Vl)-induced p53 activation: the role of phosphorylation, mdm2 and ERK." Carcinogenesis. Vol. 22, No. 5. pp. 757-762, 2001. 3. Doll R, Fishbein L, Infante P, Landrigan P, Lloyd JW, Mason TJ, Mastromatteo E, Norseth T et al. Problems of epidemiological evidence. Environ. Health Perspect. 1981;40:11- 20.
31. Kazantzis G. Role of cobalt, iron, lead, manganese, mercury, platinum, selenium and titanium in carcinogenesis. Environ. Health Perspect. 1981;40:143-161.
32. Toxic Heavy Metals: Sources and Specific Effects. (
33. Heavy Metal Toxicity. Life Extension. ( txt/t-prtcl156.htm).
34. Weyermann M, Brenner H. Factors Affecting Bone Demineralization and Blood Lead Levels of Postmenopausal Women-A Population- Based Study from Germany. Environ. Res. 1998; 76 (1):99-25(7).
35. Grizzo LT, Cordellini S. Perinatal Lead Exposure Affects Nitric Oxide and Cycloxygenase Pathways in Aorta. Toxicol. Sci. 2008; 103:207- 214.
36. Siblerud et al. Evidence that mercury from silver dental fillings may be an etiological factor in multiple sclerosis. Science of the Total Environment, 1994 Mar
37. Vimy M. Hahn LJ. Klober R. Takahashi Y. Lorscheider FL. Mercury uptake in sheep fetus from dental fillings, 32nd Annual Meeting of the Canadian Federation of Biological Societies 14-17 June 1989 and 2nd Meeting of the International Society for Trace Element Research in Humans 8/89
38. Clarkson TW, Magos L, Greenwood MR: The transport of elemental mercury into fetal tissues. Biol Neonate 21:239-44, 1972
39. University of Pennsylvania Health System. Death among children and adolescents. (; accessed 6/26/07).
40. Ejaz ul Islam, Xiao-e Yang, Zhen-li He, Qaisar Mahmood. Assessing potential dietary toxicity of heavy metals in selected vegetables and food crops. J Zhejiang Univ. Sci. B. 2007 January; 8(1):1-13.


When an effective modality becomes available to the public that has been well documented in scientific studies and literature, adopted by a growing number of wholistic physicians, is safe, not costly, saves lives and has the raving support from the majority of its recipients, common sense would lead us to believe that it would be made public and supported by those health care institutions who we expect are looking out for our best health interests.


There are over 60,000 manmade chemicals in our food, air and water. There are over 130 in our food supply alone. These include cadmium, lead, arsenic, mercury, zinc, chromium, copper, nickel and aluminum; they are present in amounts that can lodge in the tissues and interrupt the enzyme activity of that tissue and its basic metabolic function. Chelation removes these; it is a free radical scavenger, and in effect, the body is then able to rejuvenate itself.

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