Detoxamin (CaNa₂EDTA) is a rectal, time-release suppository that binds and removes or decreases toxic heavy metal contamination. It comes in four strengths: 500mg, 750mg, 1000mg and 1500mg. Detoxamin uses Calcium Disodium EDTA, a synthetic amino acid, in a suppository form as a chelating agent in a proprietary natural base with a time-release effect. Each suppository dissolves at body temperature and gradually spreads over the lining of the lower rectum where it is absorbed into the bloodstream.
One Detoxamin suppository is inserted every other evening prior to bedtime. It is suggested to eat a protein-rich meal with a low sugar content 3-4 hours prior to bedtime before Detoxamin is taken. Recommended treatment should be repeated for a 3-6 month period. Detoxamin is designed to remove toxic metals but may also remove some essential elements, therefor a good vitamin/mineral supplement must be taken during treatment.
We recommend taking Health Genesis (or similar), our own high dose multiple vitamin, mineral and trace mineral supplement each day you are taking Detoxamin, except on the nights you are using Detoxamin. Taking your supplements earlier in the day on those nights helps separate your supplements and Detoxamin. This also applies to any medication you might be taking.
REMOVE the Detoxamin Suppository from the plastic shell by pulling apart the flaps on one end, the suppository will reveal itself. Moisten Detoxamin with a few drops of water and insert the flat end first into the rectum, just past the sphincter muscle.
WAIT at least 3 hours after eating before using.
USE Detoxamin just before bedtime. Eating early in the evening is recommended, wait at least 3 hours after eating before taking. Use along with a good multi-vitamin, multi mineral supplement. We recommend using our own Health Genesis, it’s specially formulated to use along with Detoxamin. Use the restroom prior to using, and be sure your hands are clean.
TAKE vitamins and minerals each day.
TAKE your multi vitamin supplements each day you are taking Detoxamin, except on the nights you are using Detoxamin. Taking your supplements earlier in the day on those nights will help separate your supplements and Detoxamin. Avoid using clays or charcoals while using Detoxamin. Drink plenty of water.
STORE in a dry cool place, do not freeze.
Chelation comes from the Greek word “claw,” meaning “to grab,” which is exactly what EDTA does. When a molecule of EDTA travels through the bloodstream and gets near a toxic metal such as lead or mercury, it grabs the destructive particle and binds tightly with it, pulling it out of the membrane or body tissue it was embedded in.
NO RE-DISTRIBUTION OF METALS
EDTA seizes a positively charged metal ion and surrounds it. This action inactivates the metal, then the body safely eliminates the bound compound, primarily via the kidneys. To visualize this concept, imagine pinching a marble between the thumb and forefinger, the marble being the metal ion and the thumb and forefinger being the chelating agent.
Because EDTA has an affinity to heavy particles, it can attract and bind to heavy metals. The toxic ion and the amino acid connect and then–because the body regards the EDTA as a foreign substance, it sends it to the kidney for elimination. Both the EDTA and the heavy metals get a free ride into the toilet.
EDTA goes in EDTA, and comes out EDTA, it is NOT metabolised or broken down, accomplishing all stages of Detoxification. EDTA has been proven to protect cell membranes, DNA and enzyme systems by reducing the destructive effects of free radicals.
PREVENT OXIDATION OF BODY TISSUES
Free radicals are reactive molecules that are unstable because they are missing an electron. In an effort to replace their lost electron, they frantically bump into and damage the molecules that make up the cells in your body. In the process, they cause oxidation of body tissues. When a free radical comes in contact with the inner lining of your arteries, microscopic injuries result. This process is called lipid peroxidation (the process that causes fats to become rancid) and is recognized as one of the underlying causes of atherosclerosis. Eventually the build-up of fat, cholesterol, toxic metals and other substances at the site of injury narrows the arteries. The key is to neutralize free radicals before they damage your arteries.
1. “Questions & Answers: The NIH Trial of EDTA Chelation Therapy for Coronary Artery Disease” 2002
2. Waters RS, Bryden NA et al “EDTA chelation effects on urinary losses of cadmium, calcium, chromium, cobalt, copper, lead, magnesium and zinc” Biol Trac Elem Res 2001 Dec;83(3):207-221
3. Sullivan JL “Iron and the sex difference in heart disease risk” Lancet 1981 Jun 13;1(8233):1293-1294
4. Cranton EM, Frackelton JP “Free Radical Pathology in Age-Associated Diseases: Treatment with EDTA Chelation, Nutrition and Antioxidants” Journal of Advancement in Medicine 1989 Spring/Summer;2(1-2)
Your bones are toxic for life. Lead and other heavy metals are stored in the bones and get re-distributed into the bloodstream. Therefore, it is highly recommended to continue maintenance with Detoxamin, this provides the ultimate in Anti-aging benefits.
→Take 3-5 suppositories over a 30-day period. When on Detoxamin maintenance one box of Detoxamin lasts 6 to 10 months. →Take proper mineral/trace mineral/vitamin replacement every day. →Detoxamin is designed to be taken at night, however some patients and physicians prefer taking a suppository in the morning after evacuation.
The data contained in Detoxamin’s groundbreaking studies have clearly demonstrated that Detoxamin, (patented EDTA formula), effectively removes toxic metals from the tissues and bones. Also with its continued high excretion levels, even after 10 days without Detoxamin is of special interest, as well as the rebound effect in the blood lead levels. Its degree reflects the high amount of stored lead in the tissue and bones and the attendant mobilization effect. Each time the blood lead level was diminished, additional lead was mobilized from the tissues and bones.
Detoxamin offers many advantages both over the expensive intravenous method of EDTA chelation. With the use of needles via the intravenous method, and risk of AIDS and other communicable blood-borne diseases, Detoxamin is becoming the logical choice over I.V. EDTA chelation and the poorly absorbed oral EDTA. The rectum has a more neutral pH and is not as acidic as the stomach, which makes this area much better for EDTA absorption because it is not buffered and has a neutral pH, unlike the stomach. It also has very little enzymatic activity, thus enzymatic degradation does not occur.
Detoxamin EDTA Suppositories are taken at night, right before you retire for the evening. This allows LESS metabolic competition for the EDTA because the body is at rest while the EDTA is working.
Detoxamin introduces LESS dosage of EDTA, but it is done more frequently. This is just like taking vitamins, you take less more often. This fact provides better EDTA assimilation.
Almost all the blood from the rectum makes its way to the superior hemorrhoidal veins, a tributary of the portal system. The lower and middle hemorrhoidal veins BYPASS the liver and do not undergo first pass metabolism, therefore the EDTA in Detoxamin is not being filtered through the liver first, making the EDTA more productive in Detoxamin.
Detoxamin introduces EDTA directly into the systemic circulation and lymphatic system.
Detoxamin is also far safer than IV chelation because the EDTA in Detoxamin travels through the body MUCH SLOWER, not putting the same burden on the liver and kidney.
Each 3 Detoxamin suppositories are medically equal to 1 IV treatment.
Detoxamin also introduces EDTA directly into the systemic circulation, efficiently bypassing the portal circulation and the liver metabolism on the first pass. Rectal absorption may also occur through the lymphatic system and, in some cases, largely through the blood via the vena cava.
It is also important to note that the EDTA in the form of Calcium Disodium EDTA will not remove essential Calcium but indirectly remove the unwanted stores of calcifications that promote atherosclerosis.
Detoxamin suppositories remain solid below 76°F, so keep them in a cool place to prevent melting. If necessary, any broken or bubbled suppositories can be melted and reformed in the fridge.
If soft, we suggest placing the Detoxamin suppository in the refrigerator for about 10 minutes before use, to firm up the suppository before usage. Use the restroom prior to using, and be sure your hands are clean.
To open the suppository, separate one shell from the rest, then gently peel the flat plastic tabs apart to reveal the suppository inside the shell.
Detoxamin studies have shown that there is continued high excretion levels, even after 10 days without Detoxamin!
Also very unique and interesting science is the REBOUND EFFECT in the blood levels, its degree reflects the HIGH AMOUNT of stored metals in the tissue and bones and the attendant mobilization effect.
–Every time blood levels are diminished, ADDITIONAL toxic metals are mobilized from the tissues and bones.
Both EDTA and Glutathione are poorly absorbed when taken orally. But now, with this powerful formula, you can get all the powerful benefits of both EDTA and Glutathione at the highest level. You see, bio-availability is the key to performance.
Intracellular Energy Production – Mitochondria are the cell’s fuel energy source and consume more molecular oxygen than other organelles within the cytosol. This creates Reactive Oxygen Species (ROS) which generate more oxidative stress. This is a reason why mitochondria are a main target for GSH to neutralise ROS and reduce oxidative stress. Entry and replenishment of GSH into the mitochondria is a critical step in maintaining intracellular health
Antioxidant –the body’s master antioxidant, our bodies depend on it for the removal of toxins. Other antioxidants in our body depend on it to function properly.
Detoxification – detoxifies a large number of pollutants by binding to carcinogens, heavy metals, herbicides, pesticides and radiation by forming a soluble compound with the toxin that can then be excreted through the urine or bile.
Immune System – is at the heart of all immune function. Healthy growth and activity of immune cells depends on the availability of GSH. The protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them. Raising and maintaining your levels can help minimize the risk of diseases.
Increased Energy – Our energy levels are a result of many factors – everything from the biochemical reactions taking place within our cells, to muscle function and even your sense of well-being. Glutathione enables the mitochondria of a cell to remain fully charged, enhancing muscle strength and endurance. Clinical trials have shown that lowering Glutathione in the mitochondria results in cell death.
Repair – Our body is constantly under attack from free radicals, some from external sources and some generated in our own body. Free radicals attack the nearest stable molecule, “stealing” its electron. A molecule that loses an electron then becomes a free radical itself and attacks the next nearest stable molecule, this begins a chain reaction. Once the reaction is started it can cascade through hundreds of molecules. Glutathione performs a vital role in repairing the damaged DNA by replacing the missing electron. Normal to elevated Glutathione keeps the repair of our cells at a maximum and reduces the number of cell mutations that would occur otherwise.
Glutathione is regarded as a very valuable cell protector, via its direct effects on the quenching of reactive hydroxyl free radicals, other oxygen-derived free radicals and DNA damaging oxidative stressors and other biomolecules.
Glutathione is the primary defender of the eye tissues and the skin against radiation related damage and supplies the key biochemical foundations for cytochrome P450 enzymatically derived detoxification in the liver, kidneys, lungs, intestinal epithelia and other organs. Whilst it is employed by many rate limiting biochemical steps in the body our understanding of its role in the immune system management of cytokine driven inflammation is only just evolving. This represents an area of increasing research as the role of the mucosal immune system becomes attributed to persistent Para Inflammation and the degenerative conditions associated with it.
Kidd PM. Glutathione: Systemic protectant against oxidative and free radical damage. Altern Med Rev 1997;1:155-176.
Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C. Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3071-6.
Fernández-Checa JC, Kaplowitz N, García-Ruiz C. GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect; Am J Physiol. 1997 Jul;273(1 Pt 1):G7-17.
Fernández-Checa JC, García-Ruiz C, Colell A, Morales A, Marí M, Miranda M, Ardite E. Oxidative stress: role of mitochondria and protection by glutathione. Biofactors. 1998;8(1-2):7-11.
Detoxamin removes most harmful metal toxins, safely and effectively. Detoxamin is taken at night prior to bedtime, each Detoxamin suppository contains Calcium-disodium EDTA, and is made in a proprietary base, (melts on body contact), which is very therapeutic for the rectal mucosa and the colon wall.
According to Dr. Bruce Halstead MD, Scientific Advisor to Detoxamin, “The Ca-sodium form is able to bond (chelate) effectively because it does not lower the blood pH to a level that would prohibit the bonding action. The Ca added to the salt is important in this MOA (mode of administration) as it buffers the acidic quality of the active ingredient keeping the suppository from being abrasive to the mucous membrane of the rectum area. Ca-disodium EDTA has both a scientific justification for therapeutic effectiveness as well as a clinical history of effectiveness.
Detoxamin, because most people just don’t have the time or money for IV chelation. They’re not only 70% less than I.V. chelation, but they’re as effective too.
Published medical studies prove Detoxamin EDTA Suppositories delivers approximately 40 percent of what an IV dose offers, and is the most medically similar to the traditional IV chelation therapy in the world.
Detoxamin: An Easier Way To Remove The Metals. What was once a time- consuming, prescriptive treatment costing thousands of dollars is now available to you in the privacy of your own home. Detoxamin EDTA suppositories are the only product of it’s kind proven in published research.
You simply take Detoxamin chelation supplements at night before sleep. And nighttime detoxification is the most efficient, since that’s when the oxidative stress load on the body is at its minimum, and the immune system’s healing mechanisms are working at maximum.
Where intravenous chelation takes hours of sitting in one spot (a real infringement on a person’s time), you use Detoxamin suppositories in the convenience and privacy of your own home. It eliminates painful, inconvenient, expensive, and very time consuming doctor visits and heavy metal detox symptoms associated with I.V.
The body has need for approximately 70 friendly trace element heavy metals, but there are another 12 poisonous heavy metals, such as Lead, Mercury, Aluminum, Arsenic, Cadmium, Nickel, etc., that act as poisonous interference to the enzyme systems and metabolism of the body.
Metals that are ALWAYS toxic and should never be ingested include the following: mercury, antimony, arsenic, beryllium, bismuth, cadmium, copper, lead, nickel, platinum, thallium, tungsten, uranium, and aluminum
Ca-EDTA is more attracted to some elements than others. This is a list of what EDTA is attracted to, in order of highest attraction to lower. This list was comprised by research published by Saul Green and Wallace Sampson in 2002. From studies, we also know EDTA has an affinity for Arsenic and Uranium, though we do not know where they fall in the line of affinity.
“The Ca-sodium form is able to bond (chelate) effectively because it does not lower the blood pH to a level that would prohibit the bonding action. The Ca added to the salt is important in this MOA (mode of administration) as it buffers the acidic quality of the active ingredient keeping the suppository from being abrasive to the mucous membrane of the rectum area. Ca-disodium EDTA has both a scientific justification for therapeutic effectiveness as well as a clinical history of effectiveness.” Dr. Bruce Halstead MD, Scientific Advisor to Detoxamin
YES! Detoxamin is 70% less than the IV EDTA chelation method.
1) Detoxamin EDTA Suppositories are taken at night, right before you retire for the evening. This allows LESS metabolic competition for the EDTA because the body is at rest while the EDTA is working. 2) Detoxamin introduces LESS dosage of EDTA, but it is done more frequently. This is just like taking vitamins, you take less more often. This fact provides better EDTA assimilation. 3) Almost all the blood from the rectum makes its way to the superior hemorrhoidal veins, a tributary of the portal system. The lower and middle hemorrhoidal veins BYPASS the liver and do not undergo first pass metabolism, therefore the EDTA in Detoxamin is not being filtered through the liver first, making the EDTA more productive in Detoxamin. 4) Detoxamin introduces EDTA directly into the systemic circulation and lymphatic system. 5) Detoxamin is also far safer than IV chelation because the EDTA in Detoxamin travels through the body MUCH SLOWER, not putting the same burden on the liver and kidney. 6) Each 3 Detoxamin suppositories are medically equal to 1 IV treatment.
Cadmium is a metallic toxin of great environmental and occupational concern. Cadmium exposure has been associated with human prostatic cancer in some, but not all, epidemiologic studies. Some studies indicate that tissue levels of cadmium in the human prostate correlate with malignant disease.
Cadmium and prostate cancer:
M P Waalkes 1, S Rehm