How To Use Detoxamin


Detoxamin is taken every other night, and works gently while you sleep. Take right before bedtime. For more severe cases, you may take Detoxamin daily. For best results we recommend using 3 jars of Detoxamin (90 Detoxamin Suppositories) over 180 days (6 months).


Take vitamin B6 everyday (100 mg daily). And take all other supplementation on the off days (the off days are when you're not taking Detoxamin), providing less competition between the removal of toxins and the replacement of the essentials.


The recommended supplements to use are, NT Factor® Lipids Powder and NT Factor® Youthful Energy (in stock). Plus Magnesium, Zinc, Selenium, Vitamin D, Vitamin B6, quality high dose Multi-vitamin, mineral, trace mineral (Iron-free), and Systemic enzymes. Also recommended is Cod Liver Oil.

750MG / For up to 175lbs
1000MG / For 175 to 200lbs
1500MG / For 200lbs and up

750MG / For up to 175lbs
1000MG / For 175 to 200lbs
1500MG / For 200lbs and up


Chelation comes from the Greek word "claw," meaning "to grab," which is exactly what EDTA does. When a molecule of EDTA travels through the bloodstream and gets near a toxic metal such as lead or mercury, it grabs the destructive particle and binds tightly with it, pulling it out of the membrane or body tissue it was embedded in.

Since EDTA is an artificial amino acid, and since the body regards it as a foreign substance, the body eliminates the entire particle-the heavy particle coated with EDTA. The body can't tell that underneath the coating is some harmful material that it might be willing to keep even though it is harmful. Ultimately, both the EDTA and the toxic substance are delivered to the kidneys, which excrete them in the urine.

When a free radical comes in contact with the inner lining of your arteries, microscopic injuries result. This process is called lipid peroxidation (the process that causes fats to become rancid) and is recognized as one of the underlying causes of atherosclerosis. Eventually the build-up of fat, cholesterol, toxic metals and other substances at the site of injury narrows the arteries. The key is to neutralize free radicals before they damage your arteries.


  1. "Questions & Answers: The NIH Trial of EDTA Chelation Therapy for Coronary Artery Disease" 2002
  2. Waters RS, Bryden NA et al "EDTA chelation effects on urinary losses of cadmium, calcium, chromium, cobalt, copper, lead, magnesium and zinc" Biol Trac Elem Res 2001 Dec;83(3):207-221
  3. Sullivan JL "Iron and the sex difference in heart disease risk" Lancet 1981 Jun 13;1(8233):1293-1294
  4. Cranton EM, Frackelton JP "Free Radical Pathology in Age-Associated Diseases: Treatment with EDTA Chelation, Nutrition and Antioxidants" Journal of Advancement in Medicine 1989 Spring/Summer;2(1-2)

Time Release

Detoxamin has a time-release mechanism that allows the EDTA to absorb through the colon wall while you sleep. Almost all the blood from the rectum makes its way to the superior hemorrhoidal veins, a tributary of the portal system, so that absorption through the rectal wall carries the EDTA in Detoxamin to the portal vein. The lower and middle hemorrhoidal veins bypass the liver-and do not undergo first pass metabolism. This means that the EDTA in Detoxamin goes directly to the organs of your body without being filtered through the liver first. Because of this, the EDTA contained in Detoxamin is very productive.

Many Advantages

Detoxamin offers many advantages both over the expensive intravenous method of EDTA chelation. With the use of needles via the intravenous method, and risk of AIDS and other communicable blood-borne diseases, Detoxamin is becoming the logical choice over I.V. EDTA chelation and the poorly absorbed oral EDTA. The rectum has a more neutral pH and is not as acidic as the stomach, which makes this area much better for EDTA absorption because it is not buffered and has a neutral pH, unlike the stomach. It also has very little enzymatic activity, thus enzymatic degradation does not occur.

Direct EDTA Delivery

Detoxamin also introduces EDTA directly into the systemic circulation, efficiently bypassing the portal circulation and the liver metabolism on the first pass. Rectal absorption may also occur through the lymphatic system and, in some cases, largely through the blood via the vena cava.

Both EDTA and Glutathione are poorly absorbed when taken orally. But now, with this powerful formula, you can get all the powerful benefits of both EDTA and Glutathione at the highest level. You see, bio-availability is the key to performance. 

Glutathione Benefits:

Intracellular Energy Production - Mitochondria are the cell’s fuel energy source and consume more molecular oxygen than other organelles within the cytosol. This creates Reactive Oxygen Species (ROS) which generate more oxidative stress. This is a reason why mitochondria are a main target for GSH to neutralise ROS and reduce oxidative stress. Entry and replenishment of GSH into the mitochondria is a critical step in maintaining intracellular health

Antioxidant –the body’s master antioxidant, our bodies depend on it for the removal of toxins. Other antioxidants in our body depend on it to function properly.

Detoxification – detoxifies a large number of pollutants by binding to carcinogens, heavy metals, herbicides, pesticides and radiation by forming a soluble compound with the toxin that can then be excreted through the urine or bile.

Immune System – is at the heart of all immune function. Healthy growth and activity of immune cells depends on the availability of GSH. The protective activity of GSH is two-fold – it enhances the activity of immune cells and also functions as an antioxidant within them. Raising and maintaining your levels can help minimize the risk of diseases.

Increased Energy – Our energy levels are a result of many factors – everything from the biochemical reactions taking place within our cells, to muscle function and even your sense of well-being. Glutathione enables the mitochondria of a cell to remain fully charged, enhancing muscle strength and endurance. Clinical trials have shown that lowering Glutathione in the mitochondria results in cell death.

Repair – Our body is constantly under attack from free radicals, some from external sources and some generated in our own body. Free radicals attack the nearest stable molecule, “stealing” its electron. A molecule that loses an electron then becomes a free radical itself and attacks the next nearest stable molecule, this begins a chain reaction. Once the reaction is started it can cascade through hundreds of molecules. Glutathione performs a vital role in repairing the damaged DNA by replacing the missing electron. Normal to elevated Glutathione keeps the repair of our cells at a maximum and reduces the number of cell mutations that would occur otherwise.

Glutathione is regarded as a very valuable cell protector, via its direct effects on the quenching of reactive hydroxyl free radicals, other oxygen-derived free radicals and DNA damaging oxidative stressors and other biomolecules.

Glutathione is the primary defender of the eye tissues and the skin against radiation related damage and supplies the key biochemical foundations for cytochrome P450 enzymatically derived detoxification in the liver, kidneys, lungs, intestinal epithelia and other organs. Whilst it is employed by many rate limiting biochemical steps in the body our understanding of its role in the immune system management of cytokine driven inflammation is only just evolving. This represents an area of increasing research as the role of the mucosal immune system becomes  attributed to persistent Para Inflammation and the degenerative conditions associated with it.


Kidd PM. Glutathione: Systemic protectant against oxidative and free radical damage. Altern Med Rev 1997;1:155-176.

Peterson JD, Herzenberg LA, Vasquez K, Waltenbaugh C. Glutathione levels in antigen-presenting cells modulate Th1 versus Th2 response patterns. Proc Natl Acad Sci U S A. 1998 Mar 17;95(6):3071-6.

Fernández-Checa JC, Kaplowitz N, García-Ruiz C. GSH transport in mitochondria: defense against TNF-induced oxidative stress and alcohol-induced defect; Am J Physiol. 1997 Jul;273(1 Pt 1):G7-17.

Fernández-Checa JC, García-Ruiz C, Colell A, Morales A, Marí M, Miranda M, Ardite E. Oxidative stress: role of mitochondria and protection by glutathione. Biofactors. 1998;8(1-2):7-11.

Detoxamin removes most harmful metal toxins, safely and effectively. Detoxamin is taken at night prior to bedtime, each Detoxamin suppository contains Calcium-disodium EDTA, and is made in a proprietary base, (melts on body contact), which is very therapeutic for the rectal mucosa and the colon wall.

According to Dr. Bruce Halstead MD, Scientific Advisor to Detoxamin, "The Ca-sodium form is able to bond (chelate) effectively because it does not lower the blood pH to a level that would prohibit the bonding action. The Ca added to the salt is important in this MOA (mode of administration) as it buffers the acidic quality of the active ingredient keeping the suppository from being abrasive to the mucous membrane of the rectum area. Ca-disodium EDTA has both a scientific justification for therapeutic effectiveness as well as a clinical history of effectiveness.

Detoxamin, because most people just don't have the time or money for IV chelation. They're not only 70% less than I.V. chelation, but they're as effective too.

Published medical studies prove Detoxamin EDTA Suppositories delivers approximately 40 percent of what an IV dose offers, and is the most medically similar to the traditional IV chelation therapy in the world.

Detoxamin: An Easier Way To Remove The Metals. What was once a time- consuming, prescriptive treatment costing thousands of dollars is now available to you in the privacy of your own home. Detoxamin EDTA suppositories are the only product of it's kind proven in published research.

You simply take Detoxamin chelation supplements at night before sleep. And nighttime detoxification is the most efficient, since that's when the oxidative stress load on the body is at its minimum, and the immune system's healing mechanisms are working at maximum.

Where intravenous chelation takes hours of sitting in one spot (a real infringement on a person’s time), you use Detoxamin suppositories in the convenience and privacy of your own home. It eliminates painful, inconvenient, expensive, and very time consuming doctor visits and heavy metal detox symptoms associated with I.V.

The body has need for approximately 70 friendly trace element heavy metals, but there are another 12 poisonous heavy metals, such as Lead, Mercury, Aluminum, Arsenic, Cadmium, Nickel, etc., that act as poisonous interference to the enzyme systems and metabolism of the body.

Metals that are ALWAYS toxic and should never be ingested include the following: mercury, antimony, arsenic, beryllium, bismuth, cadmium, copper, lead, nickel, platinum, thallium, tungsten, uranium, and aluminum

Ca-EDTA is more attracted to some elements than others. This is a list of what EDTA is attracted to, in order of highest attraction to lower. This list was comprised by research published by Saul Green and Wallace Sampson in 2002. From studies, we also know EDTA has an affinity for Arsenic and Uranium, though we do not know where they fall in the line of affinity.

〉Iron (Ferric)







〉Iron (Ferrous)






"The Ca-sodium form is able to bond (chelate) effectively because it does not lower the blood pH to a level that would prohibit the bonding action. The Ca added to the salt is important in this MOA (mode of administration) as it buffers the acidic quality of the active ingredient keeping the suppository from being abrasive to the mucous membrane of the rectum area. Ca-disodium EDTA has both a scientific justification for therapeutic effectiveness as well as a clinical history of effectiveness." Dr. Bruce Halstead MD, Scientific Advisor to Detoxamin

Recommended Protocol

  • Detoxamin is taken every other night. Detoxamin administers less dosage of EDTA, but it does it more frequently.
  • All dietary supplementation, except vitamin B6 (100 mg daily) is done on the "off " day providing less competition between the removal of toxins and the replacement of the essentials.

Detoxamin Lifetime Maintenance

Detoxamin is a product for life. Your bones remain toxic for life-this is a fact. We highly recommend that you continue the therapy, as you will get exposed to harmful toxins continually. Unfortunately your bones are toxic for life and the toxins do get re-introduced into the bloodstream over time. Plus, our bone lead levels are 1000 times higher than those prior to the Industrial Age. Therefore, once you complete the first part of the therapy it is recommended to maintain your health with our monthly maintenance package. Our recommendation is to use 3-6 suppositories every month-you will receive the equivalent of approximately 2 IV EDTA chelation treatments. Using the suppositories on consecutive nights will give you consistent chelation. We are continually ingesting toxins and heavy metals on a continuing basis and Detoxamin is extremely safe, we feel that the maintenance protocol could be carried out over your lifetime.

YES! Detoxamin is 70% less than the IV EDTA chelation method.
1) Detoxamin EDTA Suppositories are taken at night, right before you retire for the evening. This allows LESS metabolic competition for the EDTA because the body is at rest while the EDTA is working. 2) Detoxamin introduces LESS dosage of EDTA, but it is done more frequently. This is just like taking vitamins, you take less more often. This fact provides better EDTA assimilation. 3) Almost all the blood from the rectum makes its way to the superior hemorrhoidal veins, a tributary of the portal system. The lower and middle hemorrhoidal veins BYPASS the liver and do not undergo first pass metabolism, therefore the EDTA in Detoxamin is not being filtered through the liver first, making the EDTA more productive in Detoxamin. 4) Detoxamin introduces EDTA directly into the systemic circulation and lymphatic system. 5) Detoxamin is also far safer than IV chelation because the EDTA in Detoxamin travels through the body MUCH SLOWER, not putting the same burden on the liver and kidney. 6) Each 3 Detoxamin suppositories are medically equal to 1 IV treatment.
It's the best choice for Gd, as Ca-EDTA is the most proven chelator in the world. Great results are due to its broad based chelation ability. 1 +1 in toxicity is not 2, but 10. This is due to the many metals you have, including lead, arsenic, and so on. The Gd will only come our when you also address all the metals - especially knowing we have 1000% more lead in our bones than people living just 100 years ago. So you must address ALL metals, the body then achieves a new level of homeostasis, as well as clear the essential detoxification pathways, so that the Gd is removed. You will be delighted by the results and benefits that Detoxamin offers.
Yes! Mercury Poisoning
The Calcium EDTA in Detoxamin has an extra chemical bond compared to the older Disodium EDTA. This gives Detoxamin EDTA an affinity for MERCURY. Mercury is also excreted from the body through the feces, because Detoxamin utilizes the colon wall for EDTA assimilation, it is a powerful Mercury chelator, making it possible to eliminate DMPS in some patients.
Our body today averages 1000 times more lead in your bones than was present before the Industrial Age, while it gets less of the essential minerals such as zinc in our excessively refined foods. It has become clear to many health professionals today that maintaining optimal health requires routine chelating and detoxifying agents such as garlic and EDTA that will continuously pull the toxins like lead, mercury, and even pesticides, etc., out of the body. This way, we are not putting the essential nutrients like vitamin E, etc., into a polluted cesspool and expecting to get the full benefits of these miraculous nutrients.

Interim Report of Clinical Observations of the Effects with Detoxamin and Supportive Combination Therapy on Prostate Conditions

Rita Ellithorpe, MD, Principle Investigator
Larry Clapp, PhD
Tony Jimenez, MD
Brett Jacques, ND
Robert Settineri MS

In an Institutional Review Board (IRB) approved study conducted at Tustin Longevity Center, thirty men between the ages of 48 to 74 exhibiting conditions of prostatitis, benign prostate hyperplasia, and prostate calcifications were enrolled in a 90-day clinical study. The interim trial examined the effects of a combination treatment of Detoxamin at 750mg given four times per week, Health Genesis vitamin/mineral complex given daily, one daily Natren's Healthy Trinity probiotic oil matrix capsule and tetracycline at 500mg given daily.

The initial 90-day observations revealed statistically significant Quality of Life (QOL) improvement in reducing the symptoms of benign prostate hyperplasia, with overall improvement in urinary conditions such as weak urinary stream, incomplete emptying of the bladder and strain upon urination. Results also showed a reduction of the frequency, intermittency and number of times the participants got up at night to urinate (nocturia). Erectile function was also improved in 27 out of 30 patients.

Toxic heavy metals were laboratory analyzed in packed red blood cells; the metals that showed statistically significant reductions were lead, cadmium and arsenic. Of the heavy metals analyzed in fecal samples, cadmium showed a significant decrease.

Blood chemistry panels were also analyzed in which high density lipids (HDL), the good cholesterol levels increased significantly over pre-treatment levels. The cholesterol to HDL ratios, low density lipids (LDL, bad cholesterol) and plaque 2 (LPPLA2), a marker that detects cardiovascular plaque significantly decreased in the majority of participants.

The researchers conducting this study are encouraged with the response to the treatment protocol for improving symptomology, removal of major toxic heavy metals and improving important cardiovascular markers with the men who are affected with debilitating prostate conditions. This study has been extended for an additional 90 days with some modifications of the protocol.

"With over seven years of medical chelation experience, I observed other toxic heavy metals such as aluminum, nickel, tungsten, uranium and beryllium and others being either decreased or excreted to large extents in my patients utilizing Detoxamin. This is extremely important for all people of all ages because of the abundance of continual toxic environmental exposure we all encounter each and every day. I am so confident of need for the removal of these metals with Detoxamin that I have chosen to devote my entire practice to instate the use of these suppositories in place of IV chelation with almost all my present and future patients. Detoxamin's gentle, safe and effective ability to remove these oxidatively damaging metals from our tissues is one of the single, most important things we can do to improve our health. I also incorporate and highly recommend the addition of Repairacell or Vital Cellular Nutrition with NT Factor to repair, rebuild and revitalized cells and tissues of the body in combination with Detoxamin for not only the majority of medical conditions but also as a preventive means to protect us against damaging toxins, improvement in health and increased quality of life as we age."

Dr. Rita Ellithorpe, MD

No, amazingly it doesn't. In some instances, Detoxamin actually enhances the uptake of various trace minerals, while lowering the total body burden of lead. The World Health Organization and advisors to the National Academy of Science recommend that EDTA be added to the diet of children in poor countries to enhance mineral absorption, particularly of iron and zinc. EDTA is never broken down in your body. It goes in and comes out as EDTA. So it's hard for it to do a lot of mischief since the only thing it's known to do is to have this compelling influence like an extremely good-looking, eligible young bachelor. All the attractive young ladies might sometime during the evening stop by to say hello. It's the same way with EDTA; every one of the metals (in the periodic chart) would say hello. But EDTA has a very strong list of preferences, which are called stability constants. It will be very inconstant with calcium, to which it says hello; you're there, goodbye. It says hello to magnesium; you're there, goodbye. It goes up to zinc and says hey, you're pretty interesting. Then it goes up to lead and says, I think you're really interesting, we could spend the evening together. And when it gets up to mercury, it says can we spend the rest of our life together. So that's kind of how it goes. On the other hand, we know that EDTA is a nonspecific chelator, and if there is not an ample supply of minerals with a higher stability constant, then EDTA could potentially remove essential minerals. It would ultimately depend on the amount of heavy metals in the system, the pH of the system, etc. If there is not much lead or mercury in the system for instance, then EDTA could remove zinc, which is rapidly excreted in the urine.
Yes, definitely! We recommend that you take the most advanced vitamin/mineral supplement, including zinc, which you can afford to protect your body from getting depleted. Because of environmental toxicity and this high stress lifestyle of ours, it's almost impossible to rely on food for all the nutrition our bodies need to stay healthy and strong. We live on devitalized food from mineral deficient soils that are packaged in boxes, picked green and stored in refrigerated compartments. And research has shown that, due to a steady decline in the nutritional quality of our food, even an adequate diet might not enable us to maintain the vitamin and mineral balance required to avoid health problems. It's vital that we enhance our diets with a wide spectrum of supplemental vitamins and minerals that can make up for nutritional deficiencies.
Detoxamin is patented method of EDTA chelation and medically equivalent to the intravenous method. Detoxamin is an unique formulation of EDTA that is manufactured into suppository form. Each box of Detoxamin (15 suppositories) is equal to 5 IV treatments. Detoxamin allows absorption of EDTA through the colon wall, the EDTA absorption rate in Detoxamin is 90 to 95%. There is no question that IV EDTA is useful, but we all live a busy life and we can't go to the doctor and have an IV every day. It's too inconvenient to see your doctor for three hours in his office, drive an hour to get to his office, day after day, lose a day of income and pay him $125 or whatever it costs, which is a significant amount of money. Detoxamin is an effective, convenient and affordable way of EDTA chelation and will finally help people with the excessive body burden of heavy metals, that we are all excessively burdened with today. Take our mercury levels, for example. In a report published in Linear Practice of Alternative Medicine (Fall, 2001, issue 2: 181-187), Poul Molher, MSc. calculated that it's typical to have approximately 40 million atoms of mercury per every cell of the body after getting amalgam fillings for several years. When you know the facts on total toxic metals that we all carry around in us today, you realize that, whatever hope we have of really making a dent with 30 or 40 IV treatments or even 100 chelation's over a lifetime, it is still simply a case of too little help being given too late. Detoxamin was created to replace the IV method of chelation to allow you to continue chelation to receive the ultimate benefits without the hassles and expense, because it is virtually impossible and too expensive for most people to keep going to the doctor's office for IV chelation.
Oral EDTA tablets are so poorly absorbed that it can never be equal to the IV method or to Detoxamin. The stomach acids virtually destroy most of the oral EDTA whereby very little of the EDTA is actually absorbed into the bloodstream-only about 5%. This is why the promoters of oral EDTA require that you undergo IV EDTA chelation periodically so that the benefits are realized. Oral EDTA is so poorly absorbed that you must take about 30 oral EDTA (500 mg) tablets to equal just one Detoxamin Suppository. It is clear to many in the health field today that we should all consider EDTA chelation therapy, Detoxamin was created so you can accomplish this without the inconvenience and hassles that makes IV chelation unreachable for most people.
EDTA has been shown to optimize nitric oxide production. This fact alone makes chelation therapy a benefit for virtually everyone. Nitric oxide (NO) protects the heart, stimulates the brain, kills bacteria, helps prevent blood clots that are the cause of most heart attacks and strokes, enhances oxygen delivery to tissues, and helps regulate blood pressure and blood flow to different organs. It is present in most living creatures and made by many different types of cells. It was a sensation when it was discovered that this simple, common air pollutant,-which is formed when nitrogen burns, for instance in automobile exhaust fumes-could exert so many important and life saving functions in our body.

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Click to call the numbers below:

+1 (800) 522-8974
+1 (619) 354-2728
The problem is that nitric oxide is so powerful that when we give it as a drug, there's a chance that, just like when we used to give you nitroglycerin to put under your tongue to dilate your arteries and stop your heart pain, you might get an explosive headache. So it's not innocuous to give you substances to get a nitroglycerin or nitric oxide-like effect. It turns out that it's wonderful if I can figure out a way to optimize your body's ability to make just its own ideal dose of nitric oxide, (which we believe Detoxamin helps you do, by detoxifying the cells that make NO). Because your body is not a fool and will not make too much, so there is no worry about over dosing you with EDTA induced NO.

Detoxamin suppositories remain solid below 76°F, so keep them in a cool place to prevent melting. If necessary, any broken or bubbled suppositories can be melted and reformed in the fridge.

If soft, we suggest placing the Detoxamin suppository in the refrigerator for about 10 minutes before use, to firm up the suppository before usage.  Use the restroom prior to using, and be  sure your hands are clean.

To open the suppository, separate one shell from the rest, then gently peel the flat plastic tabs apart to reveal the suppository inside the shell.

Our customer support is available 24 hours a day, so please feel free to contact us at anytime.

Click to call the numbers below:

+1 (800) 522-8974
+1 (619) 354-2728


Have more questions? Get in touch with a knowledgeable member of our customer support team.

  • ONGOING MAINTENANCE: Your bones are toxic for life. Lead and other heavy metals are stored in the bones and get re-distributed into the bloodstream. Therefore, it is highly recommended to continue maintenance with Detoxamin, this provides the ultimate in Anti-aging benefits.
  • Take 3-5 suppositories over a 30-day period. This is medically equal to approximately 2-EDTA IV treatments. When on Detoxamin maintenance one box of Detoxamin lasts 6 to 10 months.
  • Take proper mineral/trace mineral/vitamin replacement every day.
  • Note: Detoxamin is designed to be taken at night, however some patients and physicians prefer taking a suppository in the morning after evacuation.
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